![]() Athletes looking to improve exercise performance.Supplementing With Taurine Who Uses Taurine Supplements? However, scientists are unsure of the relationship between taurine and those genes. In rats, taurine supplementation changed protein and gene expression (production). Vitamin B6 deficiency, chemotherapy, surgical injury, heroin addiction, chronic disease, vegan and vegetarian diets, and advanced age have all been associated with taurine deficiency. It interacts with fats in cell membranes and stabilizes them, preventing structural changes to the cell. ![]() This means it controls water entry and exit in cells and stops them from changing the cell too much in size. Some people who can easily become taurine deficient include premature and newborn infants and chronic liver, heart, and kidney disease patients. Therefore, taurine is a conditionally essential amino acid for humans, and nutritionists recommend getting some from diet. Humans are able to produce taurine, but not in sufficient quantities under all conditions. Through calcium regulation properties, it helps to improve the function of cardiac, nervous and musculoskeletal tissue. Taurine plays various important roles in the body including regulation of water status in our cells, preventing oxidation in the body, and supporting calcium signaling in key organs. Yet taurine has a bad reputation because it’s a popular ingredient in unhealthy energy drinks. A taurine-rich diet can protect the body and promote longevity. Taurine is present in almost any tissue in the body and concentrated in key areas such as the heart, brain, and retina of the eye. Taurine (L-Taurine or 2-aminoethanesulfonic acid) is a sulfur-containing amino acid. Read on to learn how it is made and metabolized, the best dietary sources, and interesting interactions with genetics and health conditions here. It has a bad reputation as an energy drink additive, but it is vital for the normal functioning of the human body. Taurine is a semi-essential amino acid also called 2-aminoethanesulfonic acid. A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract. Note that each number in parentheses is a clickable link to peer-reviewed scientific studies. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. We believe that the most accurate information is found directly in the scientific source. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed.
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![]() 4 Despite the high number of plants cultivated, between 20 only eleven events of human exposure to members of these genera were reported to the Hawai‘i Poison Center, out of the total 44 anticholinergic plant exposures that were reported. Brusmansia x candida, one of the many Brugmansia plants commonly referred to Angel's trumpet,is the most commonly cultivated species within this genus. 3 There continues to be confusion regarding what genus member plants belong to therefore, case reports and poison control reports of contamination and ingestion interchange the genera. Lockwood separated the genus Datura into two sub-genera: Datura and Brusmansia. 2 The Datura and Brusmansia genera of plants are often used interchangeably due to all member plants initially being included in the genus Datura. The first Angel's trumpet plant, at that time listed as Datura arborea, was brought to Hawai‘i in 1825, aboard the HMS Blonde. Although eye contamination with the Angel's trumpet plant is self-limited and resolves within a week, the appearance of a persistently unilateral mydriatic eye can be alarming to patients and clinicians, which too often results in an unnecessary, costly workup. It is critical when obtaining a history from a patient with such a presentation to ask explicitly about any contact with plants prior to onset of symptoms. This likely explains why even brief contact with the plant can result in unintentional contamination of the eye and in mydriasis. The three active components occur in different parts of the plant, including on the small glandular hairs that cover the entire plant. The Angel's trumpet plant contains three active components which can result in mydriasis: hycosamine, atropine, and scopolamine. We report the case of a 14-year-old girl who presented to the pediatric emergency department with acute anisocoria and unilateral mydriasis after contacting an Angel's trumpet plant and who had complete resolution of symptoms four days following eye contamination. ![]() Acute anisocoria and unilateral mydriasis is physically alarming to patients and diagnostically worrisome to clinicians. How to Calculate the Accounts Receivable Turnover Ratio It is also useful for monitoring the overall level of working capital investment, and so is commonly presented to the treasurer and chief financial officer, who use it to plan funding levels. Since the accounts receivable turnover ratio is one of the better measures of accounting efficiency, it should be included in the performance metrics for the accounting department on an ongoing basis. When the ratio is excessively low, an acquirer can view this as an opportunity to apply more vigorous credit and collection practices, thereby reducing the working capital investment needed to run the business. The accounts receivable turnover ratio can be used in the analysis of a prospective acquiree. It is useful to track accounts receivable turnover on a trend line in order to see if turnover is slowing down if so, an increase in funding for the collections staff may be required, or at least a review of why turnover is worsening. It is also quite likely that a low turnover level indicates an excessive amount of bad debt. Low receivable turnover may be caused by a loose or nonexistent credit policy, an inadequate collections function, and/or a large proportion of customers having financial difficulties. ![]() ![]() A low turnover ratio represents an opportunity to collect excessively old accounts receivable that are unnecessarily tying up working capital. Understanding the Accounts Receivable Turnover RatioĪ high turnover ratio indicates a combination of a conservative credit policy and an aggressive collections department, as well as a number of high-quality customers. The ratio is used to evaluate the ability of a company to efficiently issue credit to its customers and collect funds from them in a timely manner. It is one of the most important measures of collection efficiency. ![]() Accounts receivable turnover is the number of times per year that a business collects its average accounts receivable. ![]() ![]() Lagophthalmos isn’t a dangerous condition, but it can ultimately lead to eye problems. Any epithelial defects or corneal ulcers should be carefully noticed.To get a better look at the eyes, a slit lamp exam is done which involves using a microscope and bright light.To observe any signs of damage to the eye, fluorescein eye stain test is done.They also assess the involvement of the facial nerve by the amount of force used to close the eyes. They also record how often the patient blinks, and how much the eyes close when it is done.The underlying cause of the disorder can be assessed by a doctor through the medical history and a physical exam by measuring the space between the eyelids with a ruler Graves' disease, which causes eyes to bulge forward.Overcorrection in ptosis (Droopy eyelid) repair.Eyelid surgery - Excessive removal of eyelid skin or muscle.Lyme disease, chickenpox, mumps, polio, Guillain-Barré syndrome, leprosy, diphtheria and botulism.damaged eyelids resulting from scarring from burns, injuries, or certain medical conditions, such as Stevens-Johnson syndrome, eyelid surgery, floppy eyelid syndrome.damage to the facial nerve may be due to injury, either from blunt trauma or a deep cut, stroke, Bell’s palsy(sudden weakness of the muscles in the face), tumors, especially acoustic neuromas, Möbius syndrome, autoimmune conditions, such as Guillain-Barré syndrome, cerebrovascular accidents.damage to the seventh cranial nerve, which controls the muscles in the eyelid.damage to or degeneration of any of the tissues of upper and lower eyelids. ![]() vertical shortening of the upper or lower eyelid causing incomplete closure during sleep.It can be minor (obscure lagophthalmos) or quite obvious. Some people are born with this problem and this can be considered congenital. Nocturnal lagophthalmos can be caused by several things. blurred vision due to unstable tear film.pain or irritation, especially in the morning due to increased corneal exposure.The feeling that something is rubbing against the eye (foreign body sensation).The main symptom of Nocturnal lagophthalmos is the inability to close the eyelids during sleep. Good eyelid closure may be lost due to the damage to or degeneration of any of these tissues. The upper and lower eyelids contain seven structural layers namely, 1) skin and subcutaneous tissue, 2) orbicularis oculi muscle, 3) orbital septum, 4) orbital fat, 5) muscles of retraction, 6) tarsus and 7) conjunctiva. It can lead to health problems over time causing exposure-related symptoms and if severe, causes corneal damage.Ībout 20% of people, including babies, suffer from this disorder. Nocturnal lagophthalmos is the inability to close the eyelids during sleep and it may reduce the quality of sleep. The condition in which people sleep with their eyes open is known as " nocturnal lagophthalmos”. Such a condition is called Lagophthalmos. Some people are unable to close their eyelids completely. If eyes are not closed properly, they will become dry. When eyes are closed or blinked, tears wet the eyes to keep them healthy. They control the opening and closure of the eyelid. The seventh cranial nerve (facial nerve) arising from the brain innervates both eyebrow muscle and eyelid muscle. Proper closure of the eyelid is essential to maintain a stable tear film and a healthy corneal surface. These medications include antidepressants, stimulants, and certain medications that treat anxiety. ![]() When you're drinking alcohol, be aware that it can interact with certain medications and cause side effects like dizziness, drowsiness, impaired concentration, and an increased chance of overdose, according to the National Institute of Alcohol Abuse and Alcoholism (NIAAA). ( Whether any amount of booze at all is safe for your health is debatable.) Those include both short- and long-term damage, as the Centers for Disease Control and Prevention (CDC) notes. Drink in moderation to limit hangover symptoms, as well as all the other negative health effects of booze. ![]() One drink equals 1.5 ounces (oz) of liquor or spirits, 12 oz of regular beer, or 5 oz of wine. For women, that means one drink a day, and for men, it's two drinks a day, per the U.S. The good news is you can take certain steps to prevent those symptoms if you’re planning to drink.įirst, to prevent a hangover, keep in mind that drinking in moderation is half the battle. “There are three big complications to a hangover: inflammation, because it binds to different chemical enzymes in the body and changes the way they act dehydration, because it causes you to urinate a lot and sleep deprivation, because it interrupts your sleep architecture so you’re not really getting a good night’s rest,” explains Deep Bhatt, MD, an internist at Weill Cornell Medicine in New York City. ![]() If you’ve ever had too much to drink, you know some of the morning-after consequences can be less than pleasant: queasiness, tiredness, a splitting headache, dry mouth, stomach upset, and a fuzzy memory, to name just a few. ![]() Below, take a look at some of the best clitoral stimulators and vibrators that'll buzz, rumble, and suck to your liking. This is one of the most pleasurable areas of the body, so make the most of it with a new clit-focused toy. Uninterrupted connection between the Toy, Remote, and App using AnkorLink technology. Dual motor vibrator for couples with Squeeze remote & touch-sense control. Believe us, once you find the combination(s) that fit your sexual preferences, you'll be thankful for all the oh-mazing possibilities. We-Vibe Vector 139 at WeVibe Material: Silicone and ABS plastic Battery Life: 2 hours How to Use: Hold the on/off button for two seconds to turn the toy on or off. We-Vibe Chorus Couples Vibrator Remote & App Controlled Wearable Vibrating Smart Sex. Whatever you go for, just make sure it has a couple of patterns and intensity options to flip through. You can even add penetration into the mix by grabbing a rabbit vibrator if you'd like. LOVENSE Lush 3 Bullet Vibrator, Upgraded Wearable Bluetooth Stimulator for Female Adult Toys, Mini Egg Style Vibrator Bullet for Women Vibrating Ball, Small Pink Remote Control Vibrating Machine 4. Level up your sexual plays with this hi-tech vibe Lovense Lush Gen 3 App-Controlled Vibrator is ideal for erotic cam performers, long-distance lovers. Or, you can stick to classic sonic vibrations with a wand or bullet vibrator. If you enjoy cunnilingus, grab an air-pulsating vibrator, which mimics the feel of sucking on your clitoral hood. There are thousands of vibrators, stimulators, and clit-suction sex toys on the market, so how do you figure out which one is prime for clit stimulation? Well, we've got some good news for you: most vibes, even the insertable ones, can actually be used on your clit. "This is why it is so responsive to stimulation," she says. "The internal part of the clitoris surrounds the vaginal canal through the corpora cavernosa (the same erectile tissue that forms a penis)." She adds that the clit is similar to a penis in terms of sensitivity and has about 8,000 sensory nerve endings. "The external clitoris is located above the urethra and where the bilateral inner labia meet," says Dr. Grover notes that it's actually just the beginning of this sensitive zone. Though most people refer to the bean-shaped area at the upper crest of the vulva as the clitoris, Dr. This study isn't the only thing backing up the orgasmic power of the clit: New York City-based board-certified obstetrician-gynecologist Monica Grover, MD says that the clitoris is actually the main source of pleasure for those with vulvas. Meanwhile, 36 percent said that, while they can orgasm from penetrative sex, their orgasms felt way better when their clit is stimulated during it. But for people who can only (or simply prefer to) orgasm through clitoral stimulation and for those in search of sex toys that offer a sensation akin to oral sex, there are more options than ever.Īccording to a 2015 study published in the Journal of Sex & Marital Therapy, just 18 percent of women participating reported climaxing during penetrative sex alone. Yes, there are tons of sex toys made for G-spot stimulation like rabbit vibrators and the classic silicone dildo. I just knew it when I saw it.Lovers may come and go, but you can always count on trusty clitoral vibrators and stimulators to get you off whenever you’d like. It had to feel like it came from this store in a small town. I didn’t find anything that felt right to me. “I had looked at vintage stuff all over the world. The Lovense Lush 3 wearable vibrator is a Bluetooth controlled wearable vibe Enjoy hands-free G-spot stimulation from powerful vibrations, as the Lush 3. “I had been looking for that dress or thinking how I was going to make it,” Atwood said. When Wednesday dances to the Cramps’ “Goo Goo Muck” at the school’s ball, the Rave’N, an internet sensation was born. The ruffled, semi-sheer dress she wears to a school dance was plucked from the window of the Alaïa boutique on New Bond Street in London. Her lace-up combat boots debuted at Prada’s Addams-esque fall 2019 show on models with pigtails like Wednesday’s. ![]() Wednesday’s custom, black-striped school uniform has made a convincing argument for modesty with her mid-calf length pleated skirt and functional chunky-sole Prada oxfords.Ītwood gave Wednesday a touch of high-fashion glamour with high-end pieces. With a costume workroom functioning full speed throughout the fall and winter of 2021 in Romania, Atwood created and tailored costumes for each character, including the Nevermore Academy purple-striped uniforms. ![]() 5 Hertz Headache Relief Meditation Music for Relaxation Delta. 28 Hertz - Meditation Music for Recovering Alcoholics Choose price 28 Hertz - Meditation Music for Recovering Alcoholics Delta. Alpha 9.8 Hz Meditation Music for Enhanced Alertness During Critical Thinking Activities Alpha 9.8 Hz Meditation Music for Enhanced Alertness During Critical Thinking Activities Choose price.Now, the average person can use brainwave meditation music to access similar physiological states - the spiritual aspect of the meditation practice is up to you to explore. The results were intriguing, to say the least. At that time many studies were performed in order to substantiate from a scientific perspective the amazing effects credited to meditation. On a physical, scientific plane, the results are strikingly similar.īrainwave meditation has its roots in the seventies when Transcendental Meditation (TM) was in vogue (remember the Beatles – Maharishi connection?). One of the most recent results of these researches is the observation of the brain frequency states reached by people new to meditation using brainwave meditation music when compared to meditation experts who have spent decades practicing. The positive effects of relaxation, mindfulness and meditation have scientists and medical doctors interested in studying all the aspects of meditation. Brainwave meditation music provides a way for people who don't have years to spend perfecting meditation techniques to experience some of the positive effects that can be scientifically measured. Meditation has been practiced since the dawn of time and today in our busy, evolving world, meditation is just as important as always. We can add to this the fact that a good number of larger, old school BlackBerry shops developed in-house, "behind the firewall" apps to expose internal systems data on BlackBerry handsets. Each quarter BlackBerry currently adds between 10,000 and 15,000 new apps to the BlackBerry World catalogue just for old school BlackBerry OS 7 devices. What I hadn't realised was how popular the BlackBerry apps ecosystem was before BlackBerry 10. Over the past two years whilst BlackBerry has been rebooting, the company has put a staggering amount of effort into schmoozing developers into developing apps for the platform. BlackBerry provides tools to do this and the process is very easy. The actual process of moving an Android app onto BlackBerry 10 (and PlayBook, incidentally) isn't so much "conversion" as "re-packaging". But it does create a problem for BlackBerry. An app is an app, and as a user if I like an app I'm not sure if I care too much whether it's a full-blown BlackBerry 10 app or an Android app. At the current run rate where they're adding about a thousand apps per day, that suggests about 13,000-odd of the apps in the catalogue are actually Android apps. In fact, as of the time of writing only 17 percent of the catalogue are repackaged Android apps. This is a runtime that allows Android apps to run on BlackBerry 10 as if they're normal application. BlackBerry 10, like PlayBook before it, has an "Android Player". There's also a perception that the catalogue is very "Android heavy". ![]() That catalogue has some problems - most notably that apps are of a certain relatively low quality and utility, and that virtually all of hero apps that contribute significantly to the dominant platforms (iOS and Android) are missing. We know that BlackBerry 10 launched with an BlackBerry World catalogue that was 70,000 apps strong. ![]() Last Wednesday, BlackBerry made the transition from being a company that was developing a new smartphone platform to a company that actually has a smartphone platform out in the market. Allowing you to amplify your human input at three different levels of electric assist. The Metro is designed to give you options of either simple throttle or pedal assist power. But it does have some superficial dings and scratches since it was used in our rental program. This Metro rides like new thanks to the service department at the IZIP Store. Making it the most attractive cargo bike on the market. The M etro can be a true car alternative with its integrated front basket and sturdy rear rack. We are selling this used IZIP Metro electric bicycle from our rental fleet at the IZIP Store to make room for 2013 models. Double Chainguard, Hi-impact Non-Slip Pedals NET WEIGHT- 57 lbs/ 26 kg BATTERY LIFE- 500 c Fender and Rack Mounts CRANKS AND PEDALS- Alloy 44T Crankset. Easy Access Charger Port in Removable Battery Pack, Twist Throttle with Battery Gauge SADDLE- Velo Suspension Comfort and Micro-Adjust Post FRAME- Exclusive Currie Aluminum Comfort Design. ![]() Stitched Leather Cruiser Grips FORKS- Chromoly Unicrown with Disc Brake Mounts USER CONTROLS- Power and PAS/TAG Switches Conveniently Mounted on the Handlebar. QR Front TIRES- Kenda Kiniption 26” x 2.3” Slime Self-Sealing Flat Tire Prevention System HANDLEBAR/ STEM- Moto Bar and 4-bolt Ahead Type Stem. Shimano Acera Rear Derailleur, SRAM Grip Shift, 7-Speed Drivetrain BRAKES- Avid BB5 Disc with Alloy Motor Inhibit Levers WHEELS- Alex 26" Double Wall Alloy Rims with Stainless Steel Spokes. Rider Input and Terrain Contingent) DRIVE- Exclusive Currie Electro-Drive® Geared Hub Motor. ![]() Rider Input and Terrain Contingent) RANGE- 20- 30 Miles/ 32- 48 km with Normal Pedaling(Rider Weight. 36 Volt Fully Potted with Power Gauge Function TOP SPEED- 20mph/ 32km/h(Rider Weight. Rear Rack Mounted, Rechargeable Cells, Advanced BMS CHARGE SYSTEM- UL Listed Currie Smart Charger with LED Status Display CONTROLLER- Exclusive Currie Electro-Drive®. 18 Nm rated torque, 500 Watts BATTERY- EV Rated Li-ion type 36V11.4Ah 410Wh. Can you afford to not have one? MOTOR- Exclusive Alloy Shell 500W DC Brushless Geared Hub Motor MOTOR SPECIFICATIONS- 40 Nm peak torque. Rider Input and Terrain Contingent) Twist and Go(TAG) and Pedal Assist System(PAS) for added versatility Ride one and you'll see why your only option is a Currie Izip Electric Bike! Easily commute to and from work without breaking a sweat. more up to 20 mph/32 km/h and range up to 20-30 miles/32-48 km with normal rider pedaling. Check out more colors and other great bike stuff at our Key Features Upright position with comfortable saddle for rider ease Real transportation at speeds.
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